Dr. Snodgrass and Dr. Bush reported the first study using testosterone before hypospadias repair based on specific measurements of the penis. They found the standard dose of testosterone was not enough to grow the penis in most boys with proximal hypospadias compared to those with distal hypospadias. They no longer use testosterone therapy in boys with hypospadias. Data shows it may impair wound healing.
Objective Use of Testosterone Reveals Androgen Insensitivity in Patients with Proximal Hypospadias